For Dogs over 25kg. Advantage® 100 Flea Adulticide will control fleas on dogs within 1 day of treatment and will continue to protect the dog from further flea infestation for at least 4 weeks. Reinfestation from the emergence of new fleas in the environment may continue to occur for 6 weeks or longer after treatment is initiated. Reapply every 4 weeks for continual pest control in situations where there is an ongoing risk of pest infestation. Treatment must only be repeated if pest problem reoccurs. If re-treatment becomes necessary earlier than 4 weeks, do not retreat more than once weekly.